Cooperative catalytic reactions using organocatalysts and transition metal catalysts: enantioselective propargylic alkylation of propargylic esters with aldehydes |
| |
| Authors: | Yoshida Akiko Ikeda Masahiro Hattori Gaku Miyake Yoshihiro Nishibayashi Yoshiaki |
| |
| Affiliation: | Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113-8656, Japan. |
| |
| Abstract: | The enantioselective propargylic alkylation of propargylic esters with aldehydes in the presence of a copper complex and an optically active secondary amine as cocatalysts has been found to give the corresponding propargylic alkylated products in good yields as a mixture of two diastereoisomers with a high enantioselectivity. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
