| Study on Triplex DNA by Use of Molecular “hight Switch”Complex of Ru(phen)_2(dppx)~(2+) |
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| 作者姓名： | Lian Sheng LING Zhi Ke HE* Fang CHEN Hua Shan ZHANG Yun E ZENG Department of Chemistry Wuhan University Wuhan 430072 Institute of Chemistry the Chinese Academy of Sciences Beijing 100080 |
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| 作者单位： | Lian Sheng LING，Zhi Ke HE*，Fang CHEN，Hua Shan ZHANG，Yun E ZENG Department of Chemistry，Wuhan University，Wuhan 430072 Institute of Chemistry，the Chinese Academy of Sciences，Beijing 100080 |
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| 基金项目： | the support of Alexander von Humboldt Foundation CAS K.C. Wong post-doctoral Research award fund and Natural Science Foundation of China for postdoctoral fellowship Educational Ministry of China，the National Natural Science |
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| 摘 要： | StudiesonthestructuraldiversityofDNAhavedrawnmuchattentioninrecentyears.Felsenfeldetal.1firstproposedthestructureoftriple-helixRNAandsuccessfullysynthesizedakindoftriplexRNA.Mirkinandcoworkers2discoveredatriplexDNA(H-DNA)inanacidsolutionofplasmid.Inthesameyear,Dervanetal.3attachedaman-madesingle-strandedDNAtorealgeneDNAandlocallyformedakindofinterstrandtriplex.ThiscouldbeusedtoinciseduplexDNAinaprecisemanner,showinghighpotentialforapplicationsasagenecontroller,man-maderestrictionend…
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| 关 键 词： | Ru(phen)2(dppx)2+ molecular 揕ight Switch? triplex DNA. |
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