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Plasmonic Nanobiosensor with Chain Reaction Amplification Mechanism |
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| Authors: | Lucas C. Recco Dr. Ihor Tokarev Prof. Dr. Sergiy Minko Prof. Dr. Valber A. Pedrosa |
| Affiliation: | 1. Institute of Biosciences, Department of Chemistry and Biochemistry, UNESP, Botucatu, SP (Brazil), Fax: (+55)?14‐38800576;2. Department Chemistry and Biomolecular, Clarkson University, Potsdam, NY 13699 (USA) |
| Abstract: | Herein we demonstrate a plasmonic nanobiosensor that explores chain reaction amplification mechanisms to transduce chemical signals released in biocatalytic reactions, turning optical signals into a visual spectral range. The sensor has a very simple design: gold nanoparticles resting in the surface of a grafted P2VP film. Changes in the gold nanoparticles’ position causes changes in the plasmon coupling mode. This is detected by means of a maximum absorbance shift. |
| Keywords: | biopolymerization biosensors nanotechnology plasmonic platforms polymerization |