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DABCO-promoted three-component reaction between amines, dialkyl acetylenedicarboxylates, and glyoxal
Authors:K RameshS Narayana Murthy  K KarnakarYVD Nageswar
Institution:Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad 500 607, India
Abstract:A simple and efficient three-component protocol for the synthesis of highly substituted pyrroles has been developed by using amines, DEAD/DMAD, and glyoxal, with the formation of products in good to excellent yields.
Keywords:Amines  Dimethyl/diethyl acetylenedicarboxylate  Glyoxal  DABCO  Acetonitrile
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