Following a protein kinase activity using a field-effect transistor device |
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| Authors: | Freeman Ronit Gill Ron Willner Itamar |
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| Institution: | Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel. |
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| Abstract: | The specific phosphorylation of a peptide-functionalized ion-sensitive field-effect transistor device by casein kinase II in the presence of ATP enables the electronic readout of the protein kinase activity; treatment of the phosphorylated surface with alkaline phosphatase results in the regeneration of the active sensing surface. |
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