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时间分辨光谱法用于离体人肺鳞癌,腺癌及正常组织的荧光寿命测量
引用本文:郑蔚,黄志伟.时间分辨光谱法用于离体人肺鳞癌,腺癌及正常组织的荧光寿命测量[J].光谱学与光谱分析,1997,17(3):20-23.
作者姓名:郑蔚  黄志伟
作者单位:[1]福建师范大学物理系 [2]福建师范大学实验中心
基金项目:浙江大学现代光学仪器开放实验室及福建省自然科学基金
摘    要:用Nd:YAG倍频光532.0nm泵浦DCM染料输出的632.8nm激光作激发源,通过时间分辨法测得离体人肺腺癌,鳞癌及正常组织的特征峰荧光寿命分别为5.1,5.6和6.3ns实验结果表明:肿瘤组织的荧光寿命总小于正常组织的荧光寿命,这种方法将有可能用于精确诊断和定位肿瘤。

关 键 词:腺癌  鳞癌  肺组织  肿瘤  诊断  激光荧光法

FLUORESCENCE LIFETIMES OF SQUAMOUS CARCINOMA,ADENOCARCINOMA AND NORMAL HUMAN LUNG TISSUES IN VITRO BY TIME RESOLVED FLUORESCENCE
W Zheng,Z Huang,S Xie,Z Lu,J Chen.FLUORESCENCE LIFETIMES OF SQUAMOUS CARCINOMA,ADENOCARCINOMA AND NORMAL HUMAN LUNG TISSUES IN VITRO BY TIME RESOLVED FLUORESCENCE[J].Spectroscopy and Spectral Analysis,1997,17(3):20-23.
Authors:W Zheng  Z Huang  S Xie  Z Lu  J Chen
Institution:Department of Physics, Fujian Normal University, 350007 Fuzhou.
Abstract:Using pulsed dye laser 632 8nm,lifetimes of adenocarcinoma,squamous carcinoma and normal human lung tissues in vitro have been measured by time resolved fluorescence as 5 1,5 6 and 6 3 ns respectively.Time resolved fluorescence shows that the decay time of tumor tissues is faster than that of normal tissues.The results may offer new diagnostic method to determine cancer.
Keywords:Time  resolved fluorescence    Lifetime    Adenocarcinoma    Squamous carcinoma    Lung tissue  
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