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Synthesis of phosphinic and phosphonic analogs of homoserine
Authors:Alferov  K. V.  Zhukov  Yu. N.  Khurs  E. N.  Osipova  T. I.  Khomutov  R. M.
Affiliation:(1) V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 ul. Vavilova, 117984 Moscow, Russian Federation
Abstract:A convenient procedure for the synthesis of 1-amino-3-hydroxypropylphosphinic and -phosphonic acids (analogs of homoserine) was developed. The procedure involves the reaction of salts of phosphinic and phosphonic analogs of S-methylmethionine with AcONa/AcOH followed by hydrolysis.
Keywords:analogs of homoserine  1-amino-3-hydroxypropylphosphinic and -phosphonic acids
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