(1) V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 ul. Vavilova, 117984 Moscow, Russian Federation
Abstract:
A convenient procedure for the synthesis of 1-amino-3-hydroxypropylphosphinic and -phosphonic acids (analogs of homoserine) was developed. The procedure involves the reaction of salts of phosphinic and phosphonic analogs of S-methylmethionine with AcONa/AcOH followed by hydrolysis.