Novel and efficient synthesis of N,N-dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes--potential marine fish toxin analogues. Part 2 |
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Authors: | Kumar Rajesh Gupta Arvind K Kaushik Mahabir P |
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Affiliation: | Process Technology Development Division, Defence R and D Establishment, Jhansi Road, Gwalior-474002 (MP), India. |
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Abstract: | A novel and efficient method for the synthesis of N,N-dialkylamino/O-alkyl phenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes 4 using activated silica has been developed. The reaction involves the condensation of substituted alpha-ketooxime and N,N-dialkylaminophenylphosphonohydrazides or O-alkylphenylphosphonohydrazides and gave the corresponding phosphonohydrazido oximes in excellent yields under mild conditions. |
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