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Ultrasonic activated efficient method for the cleavage of epoxides with aromatic amines
Authors:Kamal Ahmed  Adil S F  Arifuddin M
Institution:

Biotransformation Laboratory, Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad-500 007, India

Abstract:An improved protocol for the cleavage of epoxides with aromatic amines in the presence of FeCl3 promoted by ultrasonic irradiation. This new methodology provides excellent yields in short reaction times (15–25 min) at room temperature.
Keywords:Epoxide ring opening  Ultrasound  Aromatic amines  Regioselectivity  β-Amino alcohols
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