A new isochroman derivative from the marine fungus Phomopsis sp. (No. ZH-111) |
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| Authors: | Jian Xiang Yang Yiguang Chen Caihuan Huang Zhigang She Yongcheng Lin |
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| Affiliation: | (1) School of Chemistry and Chemical Engineering, Sun yat-sen University, Guangzhou, 510275, P. R. China; |
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| Abstract: | A new isochroman, (3R,4S)-3,4-dihydro-4,5,8-trihydroxy-3-methylisocoumarin (1), and two known compounds were isolated from the marine fungus Phomopsis sp. (No. ZH-111). Their structures were determined by spectroscopic methods, mainly 1D and 2D NMR. Preliminary pharmacological test revealed that compound 1 and exumolide A (3) can accelerate the growth of subintestinal vessel plexus (SIV) branches markedly and compound 2 can inhibit the growth of subintestinal vessel plexus (SIV) branches. |
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