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8-Amino guanine accelerates tetramolecular G-quadruplex formation |
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| Authors: | Gros Julien Aviñó Anna Lopez de la Osa Jaime González Carlos Lacroix Laurent Pérez Alberto Orozco Modesto Eritja Ramon Mergny Jean-Louis |
| Institution: | Muséum National d'Histoire Naturelle (MNHN) USM 503, INSERM U565, CRNS UMR 5153, 43 rue Cuvier CP26, F-75231, Paris Cedex 05, France. |
| Abstract: | We demonstrate here that 8-amino guanine () strongly accelerates quadruplex formation, which makes this nucleobase the most attractive replacement for guanine in the context of tetramolecular parallel quadruplexes. |
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