Synthesis of L-α-aminoadipyl-L-serinyl-D-valine,a naturally occuring tripeptide from the fermentation of Penicillium chrysogenum

A new tripeptide, L -α-aminoadipyl-L -seryl-D-valine has been synthesized by coupling the protected L-seryl-D -valine dipeptide with an appropriately protected L -α-aminoadipic acid ester. The free tripeptide was obtained after treatment with liquid HF and purification by HPLC.