Notiz zur Synthese von Alkyl-, Cycloalkyl- und Aryl-3-aminophenylsulfonen

Syntheses of Some Alkyl, Cycloalkyl and Aryl 3-Aminophenyl Sulfones Syntheses of alkyl ( 1a – 1i, 1m ), cycloalkyl ( 1j, 1k ) and aryl ( 1l ) 3-aminophenyl sulfones were achieved by ethanolic Béchamp-reduction of the appropriate 3-nitrophenyl sulfones ( 3a – 3m ). The alkyl ( 3a – 3i ) and cycloalkyl ( 3j, 3k ) 3-nitrophenyl sulfones were prepared via nitration of their respective sulfones ( 2a – 2k ). Methyl (3-nitrophenyl) sulfone ( 3a ) was also prepared by condensation of 3-nitrobenzenesulfinic acid ( 4 ) with bromoacetic acid to 3-nitrophenylsulfonyl-acetic acid ( 5 ) followed by decarboxylation.