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Reaction of 3,5-Carbonyl-substituted 1,4-Dihydropyridines with Hydrazine Hydrate
Authors:E. Bisenieks  J. Uldrikis  G. Duburs
Affiliation:(1) Latvian Institute of Organic Synthesis, Riga LV, 1006, USA
Abstract:The interaction of 3,5-carbonyl-substituted derivatives of 1,4-dihydropyridine and some analogs of it with hydrazine hydrate occurs with fission of the heterocycle. In the case of alkoxycarbonyl-substituted compounds a reverse Michael reaction predominates leading to fragmentation of the molecules.
Keywords:3-acyl- and 3-alkoxycarbonyl-5-oxo-1,4-dihydroindeno[1,2-b]pyridines  3,5-acyl- and 3,5-alkoxycarbonyl-1,4-dihydropyridines  pyrazole derivatives  fission of heterocycle with hydrazine
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