Mechanism of reaction of selenium elimination in diacetophenonyl selenide under the action of reduced glutathione |
| |
| Authors: | P A Poluboyarinov P P Leshchenko I Ya Moiseeva S G Kolesnikova N B Epshtein |
| |
| Institution: | 1.Penza State University of Architecture and Construction,Penza,Russia;2.Penza State University,Penza,Russia;3.National Research Nuclear University MEPhI,Obninsk,Russia |
| |
| Abstract: | Products of reaction between the organoselenium xenobiotic, diacetophenonyl selenide (1,5-diphenyl-3-selenapenta-1,5-dione), and reduced glutathione at different molar ratios and pH values were studied by HPLC and TLC. Reaction intermediates, S-(acetophenylselenyl)glutathione and glutathione selenodisulfide, and reaction products, acetophenone and hydroselenide anion, were detected. The reaction scheme proposed earlier was confirmed. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
