Synthesis,Characterization, and Crystal Structures of 4,6-Dimethoxy-2-hydroxy-3-methylbenzoic Acid and 2,4-Dimethoxy-6-hydroxy-3-methylbenzoic Acid |
| |
Authors: | K Chantrapromma S Chantrapromma R Suttirak P Ruanwas N Boonnak H-K Fun |
| |
Institution: | 1.Faculty of Science and Technology,Hatyai University,Songkhla,Thailand;2.Department of Chemistry, Faculty of Science,Prince of Songkla University,Hat-Yai,Thailand;3.Faculty of Science,Thaksin University,Muang, Songkhla,Thailand;4.X-ray Crystallography Unit, School of Physics,Universiti Sains Malaysia, USM,Penang,Malaysia |
| |
Abstract: | A synthetic route involving 4,6-dimethoxy-2-hydroxy-3-methylbenzoic acid (10) and 2,4-dimethoxy-6-hydroxy-3-methylbenzoic acid (11) has been investigated in the process of synthesis of the natural lichen substance namely, crocynol. Crystal structures of 10 and 11 were determined to confirm the ambiguous structures of the two isomers. Crystals 10 are monoclinic, sp. gr. P21/m, Z = 2. Crystals 11 are monoclinic, sp. gr. P21/c, Z = 4. In the crystal packing of 10, the molecules are arranged into chains along the a-axis formed only by van der Waals interactions, whereas in 11, the molecules are linked by O–H···O and C–H···O hydrogen bonds into chains along the b-axis and further stacked by π···π interactions with the centroid ···centroid distance of 3.6863(8) Å. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|