Enantioselective total synthesis of (-)-dactylolide |
| |
| Authors: | Louis Ignace Hungerford Natasha L Humphries Edward J McLeod Malcolm D |
| |
| Affiliation: | School of Chemistry, F11, The University of Sydney, NSW 2006, Australia. |
| |
| Abstract: | [reaction: see text] The enantioselective total synthesis of (-)-dactylolide is reported. The absolute stereochemistry of the tetrahydropyran was established by catalytic asymmetric Jacobsen hetero-Diels-Alder reaction. The remote C19 stereocenter was introduced by a sequence of chelation-controlled Grignard addition and Ireland-Claisen rearrangement. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
