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Marine Toxins with Spiroimine Rings: Total Synthesis of Pinnatoxin A
Authors:Beaumont Stéphane  Ilardi Elizabeth A  Tappin Nicholas D C  Zakarian Armen
Institution:Department of Chemistry and Biochemistry, University of California at Santa Barbara, Santa Barbara, CA 93106, USA.
Abstract:This microreview provides a compilation of synthetic approaches and total syntheses of pinnatoxin A in a survey of the literature up to early 2010. Pinnatoxin A is the first discovered and representative member of a fascinating group of potent marine toxins that share a spiroimine subunit as a unifying structural element.
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