| 硼亲和材料的研究进展 |
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| 引用本文： | 包建民,闫志英,李优鑫. 硼亲和材料的研究进展[J]. 化学通报, 2018, 81(5): 394-401 |
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| 作者姓名： | 包建民 闫志英 李优鑫 |
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| 作者单位： | 天津大学药物科学与技术学院天津化学化工协同创新中心天津市现代药物传递及功能高效化重点实验室 |
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| 基金项目： | 国家自然科学基金；天津市应用基础与前沿技术研究计划青年项目 |
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| 摘 要： | 硼亲和材料作为一种选择性分离富集顺式二羟基生物分子的功能性材料,近十几年里得到了蓬勃发展。在常规硼亲和材料的基础上,一些结构新颖、功能独特的材料逐渐出现并得到了广泛应用。本文介绍了硼亲和材料的研究进展,并总结了该类材料在硼亲和分离富集、疾病诊断、适配体筛选、药物传递和生物传感等方面的应用,最后对硼亲和材料的发展前景进行了展望。
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| 关 键 词： | 硼亲和材料 顺式二羟生物分子 综述 |
| 收稿时间： | 2017-10-25 |
| 修稿时间： | 2018-01-31 |
Research Progess in Boronate Affinity Materials |
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| BAO Jian-min,YAN Zhi-ying and LI You-xin. Research Progess in Boronate Affinity Materials[J]. Chemistry, 2018, 81(5): 394-401 |
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| Authors: | BAO Jian-min YAN Zhi-ying LI You-xin |
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| Affiliation: | Tianjin Key Laboratory for Modern Drug Delivery High-Efficiency,Collaborative Innovation Center of Tianjin Chemical Engineering,School of Pharmaceutical Science and Technology,Tianjin University,Tianjin Key Laboratory for Modern Drug Delivery High-Efficiency,Collaborative Innovation Center of Tianjin Chemical Engineering,School of Pharmaceutical Science and Technology,Tianjin University,Tianjin Key Laboratory for Modern Drug Delivery High-Efficiency,Collaborative Innovation Center of Tianjin Chemical Engineering,School of Pharmaceutical Science and Technology,Tianjin University |
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| Abstract: | As a kind of unique sorbent for selectively separating and enriching cis-diol-containing biomolecules, boronate affinity materials gain more and more attention in the last decade. Meanwhile, a variety of new materials with boronate affinity function are being developed and widely used in affinity separation, disease diagnostics, aptamer selection, drug delivery and biosensor. Finally, the development trends of boronate affinity materials are proposed. |
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| Keywords: | Boronate affinity materials cis-Diol-containing biomolecules Review |
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