Determination of epimer impurity in tetracycline with the use of optical rotary dispersion |
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| Authors: | A. S. Prishchepov E. K. Pil'ko |
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| Affiliation: | (1) Institute of Molecular and Atomic Physics, National Academy of Sciences of Belarus, 70 F. Skorina Ave., 220072 Minsk, Belarus;(2) Belarusian State Refresher-Training Institute of Medical Workers, Ministry of Health of the Republic of Belarus, Minsk, Belarus |
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| Abstract: | A method for determining the content of a 4-epitetracycline impurity in tetracycline preparations from its optical activity in methanol solutions, which contain sodium chloride, is developed. Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 66, No. 6, pp. 842–843, November–December, 1999. |
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| Keywords: | optical rotary dispersion tetracycline 4-epitetracycline |
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