Stereoselective synthesis of the Paulownia bagworm sex pheromone

According to our retrosynthesis, the main chain of the target molecule could be constructed using a C5 + C7 + C5 strategy. The key induction reaction afforded chiral methyl group moieties using different Evans templates with different configurations. Li_2 Cu Cl_4was effectively employed in the Csp~3 Csp~3 coupling protocol. The target molecular was obtained in a 12.6% overall yield with nine steps in the longest linear route.