Identification of mutaprodenafil in a dietary supplement and its subsequent synthesis |
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| Authors: | Demizu Yosuke Wakana Daigo Kamakura Hiroyuki Kurihara Masaaki Okuda Haruhiro Goda Yukihiro |
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| Affiliation: | National Institute of Health Sciences, Tokyo, Japan. |
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| Abstract: | We isolated a new illegal sildenafil analogue named mutaprodenafil from a dietary supplement for erectile dysfunction (ED) and proposed that it is an aildenafil derivative containing an imidazole moiety. We subsequently synthesized mutaprodenafil from a thioaildenafil and authenticated its structure. |
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