|
|||||
|
|
Wittig reaction of formyl-substituted organotrifluoroborates and stabilized phosphonium ylides in an aqueous medium |
|
| Authors: | Gary A. Molander Roberta A. Oliveira |
| Affiliation: | a Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323, United States b Departamento de Quimica Fundamental, Universidade Federal de Pernambuco, Recife-PE 50670-901, Brazil |
| Abstract: | The synthesis of unsaturated organotrifluoroborates using the Wittig alkenation is described. These transformations to disubstituted alkenes were achieved by using formyl-substituted organotrifluoroborates and stabilized ylides using water as a solvent. The products were isolated in moderate to excellent yields and the reaction gave preferentially the E-isomer. |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ | |