A proline-catalyzed aldol approach to the synthesis of 1-N-iminosugars of the d-glucuronic acid type |
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| Authors: | Chen Chen |
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| Institution: | State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China |
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| Abstract: | A new synthetic route to 1-N-iminosugars of glucuronic acid type (e.g., 1) has been developed employing proline-catalyzed aldol reaction as a key step. |
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| Keywords: | 1-N-Iminosugar Aldol reaction Proline-catalyzed Glucuronidase inhibitor Synthesis |
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