Enthalpy of dilution of aqueous systems containing S-trioxane and some amides. Analysis of the interaction of saccharides with amides in aqueous media

Enthalpies of dilution of aqueous systems of trioxane+formamide and trioxane+dimethylformamide have been determined at 25°C. The data have been treated in terms of the Savage-Wood additivity principle, and a first estimate of the pairwise group interaction enthalpy for-O-/CONH is presented. Systems of saccharides and amides are not amenable to the Savage-Wood treatment used in recent works. However, when treated in conjunction with all available data to yield a different set of group interaction parameters, saccharides behave more predictably. Implications of this state of affairs are considered.