测定双嘧达莫的化学发光新方法

提出了双嘧达莫与高锰酸钾和罗丹明B的化学发光新体系，并发现表面活性剂吐温-80可显著增强该体系的化学发光，据此建立了流动注射化学发光测定双嘧达莫的新方法。该方法选择性好，灵敏度高，线性范围宽，双嘧达莫在5.0×10-8～5.0×10-5g·mL-1范围内与发光信号呈线性关系，检出限1.7×10-8g·mL-1, RSD为1.1%(n=11, c_s=1.0×10-6g·mL-1双嘧达莫浓度)。

Chemiluminescence Method for Determination of Dipyridamole

A new system for the determination of dipyridamole with flow injection chemiluminescence was described. It is based on the chemiluminescence reaction of dipyridamole-potassium permanganate with rhodamine B. Tween-80 was found to be an enhancer of the chemiluminescence reaction. A method based on the enhanced chemiluminescence for dipyridamole determination has been developed. The method has high sensitivity, selectivity and good repeatability with a linear concentration range of 5.0 x 10(-8) - 5.0 x 10(-5) g x mL(-1), a detection limit of 1.7 x 10(-8) g x mL(-1) and a RSD of 1.1% (n = 11, cs = 1.0 x 10(-6) g x mL(-1)).