4,5-Dihydro-7,8-dimethoxy-1-phenyl-3H-2,3-benzodiazepin-4-one |
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Authors: | Giuseppe Bruno Francesco Nicoló Archimede Rotondo Rosaria Gitto Maria Zappalá |
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Abstract: | The title compound, C17H16N2O3, is an antagonist for AMPA/kainate receptors. The molecule has its seven-membered oxadiazole ring in a boat conformation. Asymmetry of the two methoxy bond angles is evident, with (Me)O—C—C angles of 115.45 (12) and 124.78 (13)°, and 114.67 (12) and 125.31 (12)°. A centrosymmetric dimer involving the HN—CO moieties, with an N⃛O distance of 2.876 (2) Å, graph set R(8), is further linked into chains through methoxy Csp3—H⃛N hydrogen bonds, with a C⃛N distance of 3.418 (2) Å. |
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