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New pyrazole-annulated azathioxanthenes as potential intercalators: Synthesis and structure elucidation
Authors:A. Varvaresou  A. Tsotinis  Th. Siatra-Papastaikoudi  T. Calogeropoulou
Affiliation:1. Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens, Panepistimiopoli Zografou, GR-15771 Athens, Greece;2. Institute of Organic and Pharmaceutical Chemistry, National Hellenic Research Foundation, 48 Vas. Constantinou Ave., GR-11635 Athens, Greece
Abstract:As part of our program aiming at developing efficacious intercalating agents, a new series of pyrazole-annulated azathioxanthenes 15a-e has been synthesized. Structure elucidation of 15a-e was based on their spectral data and especially the NOESY nmr spectrum of analog 15a .
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