Conducting polymer sensors for the amperometric detection of proteins in a flow system – the use of sulfonated dye counterions to induce selectivity

In this article, we have demonstrated the feasibility of using dye binding interactions for the amperometric detection of proteins at conducting polymer coated electrodes with flow injection analysis. Incorporation of appropriate dyes into the conducting polymer during synthesis enables sensitive and selective responses to be obtained. The effects of eluent pH and applied potential on the responses obtained for a range of proteins have been investigated. These parameters can be used to modify selectivity and achieve sensitivity.