A new approach for development of rugged sample preparation of metabolites of albendazole in cow milk |
| |
Authors: | Zsuzsanna Romvári Sándor Kemény György Pokol Jenö Fekete |
| |
Affiliation: | (1) Institute of General and Analytical Chemistry, Technical University of Budapest, Gellért tér 4, H-1521 Budapest, Hungary;(2) Department of Chemical Engineering, Technical University of Budapest, Budapest, Hungary |
| |
Abstract: | Sample preparation is the critical step in analysis of residues in biological samples. The development of a ragged method is time-consuming, because a huge number of parameters must be checked. To reduce the number of experiments Taguchi's method was applied in the sample preparation of metabolites of albendazole. During the experiments 11 controllable and 7 noise factors were investigated. From the influence of controllable and noise factors on recovery and standard deviation, conditions for the sample preparation and recovery could be concluded with high accuracy and reliability. |
| |
Keywords: | Optimisation Taguchi method HPLC Solid phase extraction |
本文献已被 SpringerLink 等数据库收录! |