Differential effects of AdOx on gene expression in P19 embryonal carcinoma cells |
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| Authors: | Li Yan Hai-yong Zhao Ye Zhang Yu-fei Shen |
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| Institution: | (1) National Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, 5 Dongdan Santiao, Beijing, 100005, China |
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| Abstract: | Background Pluripotent cells maintain a unique gene expression pattern and specific chromatin signature. In this study, we explored the
effect of the methyltransferase inhibitor adenosine dialdehyde (AdOx) on pluripotency maintenance and gene expression in P19
embryonal carcinoma cells. |
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