| 碳环核苷的合成研究进展 |
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| 引用本文： | 范学森,张新迎,王霞,渠桂荣. 碳环核苷的合成研究进展[J]. 有机化学, 2008, 28(11): 1888-1898 |
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| 作者姓名： | 范学森 张新迎 王霞 渠桂荣 |
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| 作者单位： | 河南师范大学化学与环境科学学院,新乡,453007 |
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| 基金项目： | 国家自然科学基金，河南省高校科技创新人才支持计划，河南省教育厅自然科学基金 |
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| 摘 要： | 碳环核苷是一类结构特殊且具有多种生物活性, 其中特别是抗病毒活性的核苷衍生物. 目前, 碳环核苷的合成及生物活性筛选已成为新药研究领域的热点之一. 综述了近年来各类碳环核苷的合成研究进展, 并对不同合成路线作了简要分析和评论.
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| 关 键 词： | 碳环核苷 合成 抗病毒活性 |
| 收稿时间： | 2007-08-04 |
| 修稿时间： | 2008-11-30 |
Progress in the Synthesis of Carbocyclic Nucleosides |
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| FAN,Xue-Sen,ZHANG,Xin-Ying,WANG,Xia,QU,Gui-Rong. Progress in the Synthesis of Carbocyclic Nucleosides[J]. Chinese Journal of Organic Chemistry, 2008, 28(11): 1888-1898 |
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| Authors: | FAN Xue-Sen ZHANG Xin-Ying WANG Xia QU Gui-Rong |
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| Affiliation: | (School of Chemical and Environmental Sciences, Henan Normal University, Xinxiang 453007) |
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| Abstract: | Carbocyclic nucleosides are nucleoside derivatives with special structures and interesting bioactivities, especially antiviral activities. In the past decades much attention has been paid to the synthesis and bioactivity screen of carbocyclic nucleosides in searching for new antiviral drugs. In this paper, the synthesis of various carbocyclic nucleosides is reviewed and different synthetic routes are analyzed briefly. |
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| Keywords: | carbocyclic nucleoside synthesis antiviral activity |
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