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Nafion-catalyzed microwave-assisted Ritter reaction: an atom-economic solvent-free synthesis of amides |
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| Authors: | Vivek Polshettiwar |
| Affiliation: | Sustainable Technology Division, National Risk Management Research Laboratory, US Environmental Protection Agency, 26 W. Martin Luther King Dr., MS 443, Cincinnati, OH 45268, USA |
| Abstract: | An atom-economic solvent-free synthesis of amides by the Ritter reaction of alcohols and nitriles under microwave irradiation is reported. This green protocol is catalyzed by solid-supported Nafion®NR50 with improved efficiency and reduced waste production. |
| Keywords: | Ritter reaction Amides Nafion® NR50 Solvent-free reaction Microwave irradiation |
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