Fluorescence detection of guanine-adenine transition by a hydrogen bond forming small compound |
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| Authors: | Yoshimoto Keitaro Xu Chun-Yan Nishizawa Seiichi Haga Takanobu Satake Hiroyuki Teramae Norio |
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| Affiliation: | Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan. |
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| Abstract: | In combination with abasic site-containing oligodeoxynucleotides, 2-amino-4-oxopteridine (pterin) can selectively recognize guanine base over other nucleobases accompanied by fluorescence quenching, which allows clear detection of a guanine-adenine transition with the naked eye. |
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