Stereoselective synthesis of versatile 2-chloromercurium-3,5-syn-dihydroxy esters via intramolecular oxymercuration |
| |
| Authors: | Carlo Bonini Maria Campaniello Valeria Videtta |
| |
| Institution: | Dipartimento di Chimica, Università degli Studi della Basilicata, Via N. Sauro 85, 85100 Potenza, Italy |
| |
| Abstract: | Regio- and stereocontrolled alkoxy mercuration of α,β-unsaturated esters allows direct access to 1,3-syn diols in good yields. Demercuration of adducts leads to 1,3 skipped dihydroxy esters, alcohols, and α-halo esters. The deprotection of acetonide with Amberlyst 15 on 1,3-syn-dihydroxy esters gives the corresponding δ-lactones. |
| |
| Keywords: | Oxymercuration 1 3-syn-Diol Demercuration Lactonization |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
