Formal synthesis of salinosporamide A using a nickel-catalyzed reductive aldol cyclization-lactonization as a key step |
| |
Authors: | Isabel Villanueva Margalef |
| |
Institution: | School of Chemistry, University of Edinburgh, Joseph Black Building, The King's Buildings, West Mains Road, Edinburgh EH9 3JJ, United Kingdom |
| |
Abstract: | Application of a sequential nickel-catalyzed reductive aldol cyclization-lactonization reaction in a short formal synthesis of salinsporamide A, a potent 20S proteasome inhibitor and anti-cancer compound, is described. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|