Synthesis of (-)-calicoferol B |
| |
| Authors: | Taber Douglass F Jiang Qin Chen Bei Zhang Wei Campbell Carlton L |
| |
| Affiliation: | Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA. taberdf@udel.edu |
| |
| Abstract: | The first total synthesis of (-)-calicoferol B (III) is described. The cyclozirconation product I, prepared in enantiomerically pure form, was converted into the CD ring chiron II. This was coupled with the aromatic A-ring, and then the side chain was constructed with control of relative and absolute configuration to complete the total synthesis of III. The first total synthesis of (-)-calicoferol B (1) is described. The cyclozirconation product 8, prepared in enantiomerically pure form, was converted into the CD ring chiron 6. This was coupled with the aromatic A-ring, and then the side chain was constructed with control of relative and absolute configuration to complete the total synthesis of 1. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
