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Characterization of a magnetic carrier encapsulating europium and ferrite nanoparticles for biomolecular recognition and imaging |
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| Authors: | Mamoru Hatakeyama Yusuke Mochizuki Yoshinori Kita Kosuke Nishio Masanori Abe Hiroshi Handa |
| Institution: | a Integrated Research Institute, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan b Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan c Graduate School of Science and Technology, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8550, Japan |
| Abstract: | In this study, FG beads (ferrite nanoparticles in the core covered with poly-(styrene-co-glycidyl methacrylate)) were made into fluorescent magnetic carriers (FMCs) containing the fluorescent substance, europium ion (Eu3+) complex. The developed FMCs showed several notable features such as high fluorescence intensity and high dispersibility in water. More importantly, FMCs did not leak Eu3+ complex. It is expected that the FMCs will be a useful tool for biomolecular recognition and imaging and contribute to advancement of a wide range of research fields, including cell biology and molecular imaging. |
| Keywords: | Fluorescent magnetic carrier Eu3+ complex Biomolecular recognition Biomolecular imaging Functional polymer |
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