| Studies on the Effects of Epimedium Extract on Erythrocytes |
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| 引用本文： | Xiao Yu ZHANG Feng Hua CHEN Ping Hui WEI Jia Zuan NI. Studies on the Effects of Epimedium Extract on Erythrocytes[J]. 中国化学快报, 2006, 17(8): 1105-1108 |
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| 作者姓名： | Xiao Yu ZHANG Feng Hua CHEN Ping Hui WEI Jia Zuan NI |
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| 作者单位： | [1]Department of Biological Engineering, College of Environment ＆ Chemical Engineering, Yanshan University, Hebei 066004 [2]Key Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 |
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| 摘 要： | Epimedium, one of representatives of traditional Chinese herb, is mainly composed of flavones and polysaccharide. It is famous for its antioxidant, antineoplastic and antiaging activities and has been widely used in the field of invigorating kidney and st…
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| 关 键 词： | AFM 淫羊藿提取物 中药 淫羊藿甙 红血球 细胞内自由二价钙离子 |
| 收稿时间： | 2006-02-13 |
Studies on the Effects of Epimedium Extract on Erythrocytes |
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| Xiao Yu ZHANG,Feng Hua CHEN,Ping Hui WEI,Jia Zuan NI. Studies on the Effects of Epimedium Extract on Erythrocytes[J]. Chinese Chemical Letters, 2006, 17(8): 1105-1108 |
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| Authors: | Xiao Yu ZHANG Feng Hua CHEN Ping Hui WEI Jia Zuan NI |
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| Abstract: | The effect of Epimedium extract (EE) on erythrocytes was investigated by atomic force microscopy (AFM). The images of the surface structures showed clear concave and progressive increase of surface roughness of erythrocyte after incubation with EE at concentration of 0.2 or 0.05 g/L, far below its critical hemolytic levels. The AFM results also indicated that the granules of the fine surface structure increased, which caused by aggregation of membrane protein. Further study showed that the change in surface topography of erythrocyte membrane might be connected with the increase of intracellular free Ca2 induced by EE. |
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| Keywords: | AFM Epimedium extract (EE) erythrocyte intracellular free Ca2 . |
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