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Electrochemical behavior of adriamycin at an electrode modified with silver nanoparticles and multi-walled carbon nanotubes, and its application |
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| Authors: | Keying Zhang Yuzhong Zhang |
| Institution: | 1. Anhui Key Laboratory of Spin Electron and Nanomaterials (Cultivating Base), Suzhou College, Suzhou, 234000, Anhui, People’s Republic of China 2. Department of Chemistry-Biology, Suzhou College, Suzhou, 234000, Anhui, People’s Republic of China 3. College of Chemistry and Materials Science, Anhui Key Laboratory of Chem-Biosensing, Anhui Normal University, Wuhu, 241000, People’s Republic of China |
| Abstract: | An electrochemical sensor has been constructed for the determination of adriamycin (ADM) that is based on a glassy carbon electrode modified with silver nanoparticles and multi-walled carbon nanotubes with carboxy groups. The modified electrode was characterized by scanning electron microscopy and exhibits a large enhancement of the differential pulse voltammetric response to ADM. Signals are linear with the concentrations of ADM in the range from 8.2?×?10?9 M to 19.0?×?10?9 M, with a detection limit of 1.7?×?10?9 M. The sensor is highly reproducible and exhibits excellent stability. It was to detect calf thymus DNA. |
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