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Pharmacophore refinement of gpIIb/IIIa antagonists based on comparative studies of antiadhesive cyclic and acyclic RGD peptides |
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| Authors: | Gerhard Müller Marion Gurrath Horst Kessler |
| Affiliation: | (1) Institut für Organische Chemie und Biochemic, Technische Universität München, Lichtenbergstrasse 4, D-85747 Garching, Germany;(2) Present address: Bayer AG, MD-IM-FA, Computational chemistry, Gebäude Q18, D-51368 Leverkusen, Germany;(3) Present address: Biopolymer Research Centre, Department of Organic Chemistry, University of Padua, Via Marzolo 1, I-35131 Padua, Italy |
| Abstract: | |
| Keywords: | Arg-Gly-Asp peptides Adhesion antagonista Peptide templates Conformational restriction Vector analysis Structure-activity relationships |
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