Synthesis of 14-epi-19-nor-22-oxa-1α,25-dihydroxyvitamin D3 |
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作者姓名: | Wei Fan Li Hai Yong Wu Key Laboratory of Drag Targeting of Education Ministry West China School of Pharmacy Sichuan University Chengdu China |
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作者单位: | Key Laboratory of Drug Targeting of Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China |
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基金项目: | This work was supported by the National Natural Science Foundation of China (No. 29972013). |
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摘 要: | The synthesis of 14-epi-19-nor-22-oxa-1α,25(OH)2D3 5 was started from diol 8 via Fall's method, oxidation, epimerization, protection, coupling with the 19-nor-A-ring 7, and then deprotection of the hydroxyl functions.
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关 键 词: | 有机化合物 合成方法 方程式 化学实验 |
收稿时间: | 4 September 2007 |
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