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Design,synthesis, cytotoxicity and molecular modeling studies of some novel fluorinated pyrazole-based heterocycles as anticancer and apoptosis-inducing agents |
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| Authors: | Fayed Eman A. Eissa Sally I. Bayoumi Ashraf H. Gohar Nirvana A. Mehany Ahmed B. M. Ammar Yousry A. |
| Affiliation: | 1.Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt ;2.Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al-Azhar University (Girls), Cairo, Egypt ;3.Faculty of Pharmacy, Al-Maarefa University for Science and Technology, Riyadh, Kingdom of Saudi Arabia ;4.Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt ;5.Department of Zoology, Faculty of Science, Al-Azhar University, Cairo, Egypt ;6.Organic Chemistry Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt ; |
| Abstract: | Molecular Diversity - 3,5-Diamino-4-(3-trifluoromethylphenyldiazenyl)-1H-pyrazole was used as a starting scaffold for the synthesis of new pyrazole-based heterocycles to study their effects on the... |
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