Pd-catalyzed cycloisomerization-allylation of 4-alkynones: synthesis of 5-homoallylfuran derivatives |
| |
| Authors: | Akio Saito |
| |
| Institution: | Laboratory of Organic Reaction Chemistry, Showa Pharmaceutical University, 3-3165 Higashi-Tamagawagakuen, Machida, Tokyo 194-8543, Japan |
| |
| Abstract: | In the presence of Pd2(dba)3-tBu3P catalyst and Cs2CO3, cycloisomerization-allylation reactions of 4-alkynone derivatives with allyl carbonates in MeCN proceed in 5-exo mode to give highly-substituted furans having homoallyl groups at 5-position. |
| |
| Keywords: | Cascade reaction Cycloisomerization Allylation syn-Oxipalladation Furan Alkynone |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
