A Convenient Palladium‐Catalyzed Carbonylative Suzuki Coupling of Aryl Halides with Formic Acid as the Carbon Monoxide Source |
| |
| Authors: | Dr Xinxin Qi Li‐Bing Jiang Hao‐Peng Li Prof?Dr Xiao‐Feng Wu |
| |
| Institution: | 1. Department of Chemistry, Zhejiang Sci‐Tech University, Xiasha Campus, Hangzhou 310018 (P.R. China);2. Leibniz‐Institut für Katalyse e.V. an der Universit?t Rostock, Albert‐Einstein‐Strasse 29a, 18059 Rostock (Germany) |
| |
| Abstract: | A practical palladium‐catalyzed carbonylative Suzuki coupling of aryl halides under carbon monoxide gas‐free conditions has been developed. Here, formic acid was utilized as the carbon monoxide source for the first time with acetic anhydride as the additive. A variety of diarylketones were produced in moderate to excellent yields from the corresponding aryl halides and arylboronic acids. |
| |
| Keywords: | carbonylation cross‐coupling heterogeneous catalysis palladium synthesis design |
|
