|
|||||
|
|
Boron Clusters as a Platform for New Materials: Synthesis of Functionalized o‐Carborane (C2B10H12) Derivatives Incorporating DNA Fragments |
|
| Authors: | Slawomir Janczak Prof. Agnieszka Olejniczak Sandra Balabańska Prof. Marcin K. Chmielewski Dr. Marius Lupu Prof. Clara Viñas Prof. Zbigniew J. Lesnikowski |
| Affiliation: | 1. Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology Polish Academy of Sciences, Lodowa 106, 92‐232 Lodz (Poland);2. Screening Laboratory, Institute of Medical Biology Polish Academy of Sciences, Lodowa 106, 92‐232 Lodz (Poland);3. Institute of Bioorganic Chemistry Polish Academy of Sciences, Noskowskiego 12/14, 61‐704 Poznan (Poland);4. Institut de Ciència de Materials de Barcelona (CSIC), Campus de la U.A.B., 08193 Bellaterra (Spain) |
| Abstract: | A synthetic strategy for functionalization of the three vertices of o‐carborane and the attachment of the obtained triped to the solid support was developed. Further functionalization of the triped with short DNA sequences by automated DNA synthesis was achieved. The proposed methodology is a first example of boron cluster chemistry on a solid support opening new perspectives in boron cluster functionalization. |
| Keywords: | boron clusters conjugates DNA nanomaterials tripeds |