Organoantimony(III)‐Containing Tungstoarsenates(III): From Controlled Assembly to Biological Activity |
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| Authors: | Peng Yang Dr Bassem S Bassil Dr Zhengguo Lin Dr Ali Haider Dr Gabriela Alfaro‐Espinoza Prof Matthias S Ullrich Prof Cristian Silvestru Prof Ulrich Kortz |
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| Institution: | 1. Department of Life Sciences and Chemistry, Jacobs University, P.O. Box 750 561, 28725 Bremen (Germany);2. Department of Chemistry, Faculty of Sciences, University of Balamand, P.O. Box 100, Tripoli (Lebanon);3. Department of Chemistry, Supramolecular Organic and Organometallic Chemistry Centre (SOOMCC), Faculty of Chemistry and Chemical Engineering, Babes‐Bolyai University, Arany Janos Str. 11, RO‐400028 Cluj‐Napoca (Romania) |
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| Abstract: | A family of three sandwich‐type, phenylantimony(III)‐containing tungstoarsenates(III), (PhSbIII){Na(H2O)}AsIII2W19O67(H2O)]11? ( 1 ), (PhSbIII)2AsIII2W19O67(H2O)]10? ( 2 ), and (PhSbIII)3(B‐α‐AsIIIW9O33)2]12? ( 3 ), have been synthesized by one‐pot procedures and isolated as hydrated alkali metal salts, Cs3K3.5Na4.5(PhSbIII){Na(H2O)}AsIII2W19O67(H2O)]?41H2O ( CsKNa ‐ 1 ), Cs4.5K5.5(PhSbIII)2AsIII2W19O67(H2O)]?35H2O ( CsK‐2 ), and Cs4.5Na7.5(PhSbIII)3(B‐α‐AsIIIW9O33)2]?42H2O ( CsNa ‐ 3 ). The number of incorporated {PhSbIII} units could be selectively tuned from one to three by careful control of the reaction parameters. The three compounds were characterized in the solid state by single‐crystal XRD, IR spectroscopy, and thermogravimetric analysis. The aqueous solution stability of sandwich polyanions 1 – 3 was also studied by multinuclear (1H, 13C, 183W) NMR spectroscopy. Effective inhibitory activity against six different kinds of bacteria was identified for all three polyanions, for which the activity increased with the number of incorporated {PhSbIII} groups. |
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| Keywords: | biological activity NMR spectroscopy organoantimony polyoxometalates sandwich complexes |
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