Organic Photocatalytic Cyclization of Polyenes: A Visible‐Light‐Mediated Radical Cascade Approach |
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| Authors: | Zhongbo Yang Han Li Dr. Long Zhang Prof. Ming‐Tian Zhang Prof. Dr. Jin‐Pei Cheng Prof. Dr. Sanzhong Luo |
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| Affiliation: | 1. Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, The Chinese Academy of Sciences, Beijing, 100190 (China), Fax: (+86)‐10‐6255‐4449http://luosz.iccas.ac.cn;2. Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, 300071 (China);3. Center of Basic Molecular Science (CBMS) Department of Chemistry, Tsinghua University, Beijing, 100084 (China) |
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| Abstract: | A visible‐light‐mediated, organic photocatalytic stereoselective radical cascade cyclization of polyprenoids is described. The desired cascade cyclization products are achieved in good yields and high stereoselectivities with eosin Y as photocatalyst in hexafluoro‐2‐propanol. The catalyst system is also suitable for 1,3‐dicarbonyl compounds, which require only catalytic amounts of LiBr to promote the formation of the corresponding enols. |
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| Keywords: | cyclization organocatalysis photocatalysis polyenes radical reactions |
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