| Abstract: | Four new cerebrosides, gynuramides I?IV ( 1 ‐ 4 ), together with 37 known compounds were isolated from the rhizome of Gynura japonica. The structures of cerebrosides 1 ‐ 4 were determined by chemical and spectroscopic examination to be: (2S,3S,4R,8E)‐2‐(R)‐2‐hydroxypentacosanoylamino]‐8‐en‐1,3,4‐octadecanetriol, (2S,3S,4R,8E)‐2‐(R)‐2‐hydroxytetracosanoylamino]‐8‐en‐1,3,4‐octadecanetriol, (2S,3S,4R,8E)‐2‐(R)‐2‐hydroxytricosanoylamino]‐8‐en‐1,3,4‐octadecanetriol, and (2S,3S,4R,8E)‐2‐(R)‐2‐hydroxydocosanoylamino]‐8‐en‐1,3,4‐octadecanetriol. |
