Synthesis of new non‐symmetrical substituted 7,7′‐bisindolizines by the direct reaction of 4,4′‐bipyridinium‐ylides with dimethyl acetylenedicarboxylate

We report here on the synthesis of some novel non‐symmetrical substituted bisindolizines by 3+2 dipolar cycloaddition reaction. New compounds were prepared by the direct reaction of isolated non‐symmetrical substituted 4,4′‐bipyridinium bisylides with dimethyl acetylenedicarboxy late (DMAD). The obtained compounds can be used as precursors of fluorescent markers in fluorometric analysis.